Hot Off The Press Proof: Gum Disease Causing Rheumatoid Arthritis
From Medscape, December 29, 2016: a report on research by Johns Hopkins University School of Medicine, Division of Rheumatology. They are finally trying to treat the cause, and not the symptoms of disease, and recognizing that autoimmune diseases are actually collateral damage diseases or infections not previously connected, as I stated in my 2014 book, The Superlongevity Rx. Just treating the symptoms with immunosuppressants is bad for your overall health, so I am extremely happy that they are looking to treat the cause for a change, thereby not contributing to your decline.
The research found a gram negative anaerobe, aggregatibacter actinomycetemcomitans (Aa) found in 62% of chronic periodontal (gum) disease cases is a probable cause of many, but not all, cases of rheumatoid arthritis. This also suggests that there are also other causes, such as Staphylococcus aureus. Both of these gum disease pathogens produce pore-forming toxins which poke holes in your cell membranes, allowing calcium to pour into them. This drives the activation of enzymes that mediate an amino acid conversion in your proteins, a process called hypercitrullination, which in turn induces antibody production against those proteins. The antibodies cause those cells with the citrullination to be removed from your system. These anticitrullination antibodies are a hallmark of rheumatoid arthritis. They are associated with the erosive joint destruction seen in people with rheumatoid arthritis as well as chronic periodontal destruction.
What we thought was an unknown cause "autoimmune" disease, rheumatoid arthritis is turning out to be an infectious disease process with collateral damage, just like periodontal disease. They are finding what was previously thought to be "periodontal only" disease organisms in the joints and elsewhere, gaining entrance via the blood supply.
I cannot stress highly enough, the need to visit a dentist regularly to keep periodontal disease suppressed, or better, out of your system. Be sure to find a dentist who rates diagnosing and treating gum disease as his/her priority for the sake of your health and longevity.